Abstract            Volume:4  Issue-3  Year-2016         Original Research Articles

Online ISSN : 2347 - 3215 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcret@gmail.com

The aims of this study was to assess the ability of Protein to Creatinine ratio from random urine samples to rule in or rule out proteinuria in patients with Chronic Kidney Disease. Chronic renal failure is a clinical syndrome resulting in the progressive loss of renal function.  The symptoms of chronic renal failure result not only from simple excretory failure but also from the onset of regulating failure, the kidney’s failure to regulate certain substances, such as sodium & water. Chronic kidney disease patients were selected on the basis of serum creatinine levels. In this study, we demonstrated that urinary creatinine very helpful for chronic renal failure. Collection of 24hr urine samples is cumbersome and prone to errors, hence analyte measurement in random urine is often proposed with correction for variation in urine flow rate by expressing results as a ratio to creatinine concentration. The tests are to be used for monitoring the level of proteinuria in established renal disease, they can then be used as surrogates for 24hr measurements

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