Abstract            Volume:8  Issue-4  Year-2020         Original Research Articles

Online ISSN : 2347 - 3215 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcret@gmail.com

Asymptomatic bacteriuria is a common condition among pregnant women and if untreated could lead to maternal and fetal complications. In addition to this, rapid emergence of antimicrobial resistance is became a major health problem and need continuous monitoring of the susceptibility patterns of pathogens. A hospital-based cross-sectional study was conducted among 290 asymptomatic pregnant women attending Saint Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia. Data were collected using systematic random sampling technique with interviewer-administered pretested questionnaire. Clean-catch midstream urine specimens were collected and microbiological investigations were performed using standard procedures. Data were analyzed by SPSS version 23. Binary and multivariable logistic regressions were used to identify predictors of asymptomatic bacteriuria. Variables having p-value ≤ 0.05 were considered as statistically significant. Out of the 290 study participants, 49(16.9%) were positive for asymptomatic bacteriuria. Escherichia coli 21(43%) and Staphylococcus aureus 10(20%) were common bacterial isolates. Most bacterial isolates were susceptible to nitrofurantoin. Most E. coli isolates were resistant to amoxicillin (86.4%). The prevalence of multi-drug resistance in all study isolates was 57.1%. Pregnant women with a history of urinary tract infection [AOR=3.11, P=0.004], history of catheterization [AOR=2.31, P=0.040], hemoglobin level less <11g/dl [AOR=10.49, P<0.0001] and natural abortion [AOR=2.36, P=0.023] were found to be statistically significant associated with asymptomatic bacteriuria. Asymptomatic bacteriuria was prevalent among pregnant women in our study area setting. Therefore, pregnant women should be screened by urine culture and treatment be guided by antimicrobial susceptibility data. Continuous local monitoring of resistance patterns is important for empirical therapy as well as for epidemiological reasons

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