Abstract            Volume:5  Issue-9  Year-2017         Original Research Articles

Online ISSN : 2347 - 3215 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcret@gmail.com

Human Immunodeficiency Virus (HIV) is one of the major threats to mankind. HIV infection is a global pandemic with numerous cases reported from many countries. The major threat to their life is not by the virus but due to these opportunistic pathogens and associated complications Infections induced by pathogenic bacteria are recognized as emerging threat to HIV/AIDS patients. Clausena dentata is a small tree belonging to the family Rutaceae with medicinal, nutritive value and volatile oils of four furanoid terpenic compounds, α-clausenan, rosefuran (γ-clausenan) and diclausenans A.In the present study, antibacterial activity of the ethanol, ethylacetate, chloroform, petroleum and acetone extracts of Clausena dentata leaf were tested against ten opportunistic bacteria isolated from the HIV/AIDS patients of Thuraiyur region of Tiruchirappalli District. Among the various solvent extracts tested, the ethanol extract showed significant antibacterial activity against most of the test bacteria. The zones of inhibition were higher in the case of Staphylococcus hominis and Enterobacter faecalis Staphylococcus haemolyticus and Klebsiella pneumoniae

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