Abstract            Volume:4  Issue-7  Year-2016         Original Research Articles

Online ISSN : 2347 - 3215 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcret@gmail.com

Bowel disorders include a large variety of diseases such as Irritable bowel syndrome (IBS) (a chronic gastrointestinal disorder characterized by abdominal pain or discomfort) and Inflammatory Bowel Diseases (IBD) (Crohn's disease and Ulcerative colitis) both associated with abnormal bowel habits results either in diarrhea, constipation or alternative cycle of both or mixed diarrhea and constipation. This study is an investigation to prove the role of Blastocystis hominis in development of IBS or IBD. A total of (608) stool samples were collected from Irritable Bowel Syndrome (IBS) patients (472), Inflammatory Bowel Diseases (IBD) as a disease control (79), and apparently healthy control group (HC) (57) of both sexes included males (372) and females (236) from Kirkuk Province-Iraq Hospital such as Azadi Teaching Hospital. All those stool samples were directly examined for Blastocystis hominis or other pathogenic agents and BMI for patients and control groups were estimated. It was showed that there was a highly significant incidence of Blastocystis hominis (33.7%) & (41.8%) (Among IBS and IBD respectively) in comparison with (12.3%) among healthy control group (P= 0.0001). Most those patients were at age group 20-40 years (47.9% and 45.6% for IBS and IBD patients respectively). Majority of IBS and IBD patients (39.4% and 34.2% for IBS & IBD respectively) complained from diarrhea in highly significant manner in comparison with control group (only 7%) (P=0.001). Furthermore, it was become clear that most IBS patients (51.3%) were over-weight with highly significant differences in comparison with IBD patients (35.4%) and HC (33.3%) (P = 0.001). It could be concluded that Blastocystis hominis play a crucial role in IBS or IBD development and increment in body weight may enhance the development of bowel disorders.

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