IJCRAR is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCRAR Articles.

INDEXED IN INDEX COPERNICUS - ICI Journals Master List 2016 - IJCRAR--ICV 2016: 81.15 For more details click here

Abstract            Volume:13  Issue-8  Year-2025         Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Physiological Regulation of Bioactive Compound Production in Medicinal Plants: A Comprehensive Review
Satyendra Thakur1, Rohit Kumar Kumawat2, Sachin Nagre3, Mrinalini Singh4 and Prashant Gigaulia5
1Department of Forest Management, MP State Forest Research Institute, Polipathar, Jabalpur (482008), India 2Young Professional II, Project Coordination Unit, Sesame & Niger, JNKVV, Jabalpur-482004, (M.P), India 3Department of Plant Physiology, JNKVV, Jabalpur-482004, (M.P), India
4PhD Scholar, Department of Biotechnology, College of Horticulture, Dr Yashwant Singh Parmar University of Horticulture and Forestry, Nauni, Solan, Himachal Pradesh. 173230
5Department of Molecular Biology and Biotechnology, CoA, JNKVV, Jabalpur482004, (M.P), India
*Corresponding author
Abstract:

Medicinal plants form the foundation of both traditional and modern healthcare systems owing to their ability to produce diverse bioactive compounds with significant therapeutic potential. The biosynthesis and accumulation of these metabolites are governed by complex physiological and biochemical processes that regulate both primary and secondary metabolism. Key physiological activities such as photosynthesis, respiration, transpiration, and nutrient assimilation not only sustain plant growth and development but also strongly influence the synthesis of pharmacologically active secondary metabolites including flavonoids, terpenoids, alkaloids, and phenolics. Plant growth regulators (PGRs)—such as auxins, cytokinins, gibberellins, jasmonic acid, and salicylic acid—play pivotal roles in modulating these physiological and metabolic pathways by mediating stress responses, cell differentiation, and secondary metabolite biosynthesis. Moreover, environmental and abiotic factors such as light, temperature, water availability and nutrient status further interact with PGR signaling networks, thereby shaping the metabolic outcomes and therapeutic quality of medicinal plants. This review synthesizes recent advances in understanding the physiological and hormonal regulation of bioactive compound production in medicinal plants, emphasizing the integration of metabolism, environmental adaptation, and signaling mechanisms. A comprehensive understanding of these processes can guide the development of improved cultivation practices, biotechnological interventions, and metabolic engineering strategies for the sustainable enhancement of medicinal plant resources.

Keywords: Medicinal plants, physiological regulation; secondary metabolism; bioactive compounds
Download this article as Download

How to cite this article:

Satyendra Thakur, Rohit Kumar Kumawat, Sachin Nagre, Mrinalini Singh and Prashant Gigaulia. 2025. Physiological Regulation of Bioactive Compound Production in Medicinal Plants: A Comprehensive Review.Int.J.Curr.Res.Aca.Rev. 13(8): 145-151
doi: https://doi.org/10.20546/ijcrar.2025.1308.011
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.