Abstract            Volume:13  Issue-5  Year-2025         Original Research Articles

Online ISSN : 2347 - 3215 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcret@gmail.com

Semen morphology is a key parameter in male fertility assessment, traditionally evaluated through manual microscopic techniques. However, advancements in automated analysis systems such as the Computer-Assisted Semen Analysis (CASA), particularly the PRIME SPERM CASA system, have introduced new standards for objectivity and consistency. This study compares the accuracy, reproducibility, and diagnostic value of manual semen morphology reports with those generated by the PRIME SPERM CASA system. A total of semen samples were evaluated using both methods. The results highlight significant differences in morphology classification, with CASA demonstrating greater consistency and reduced observer variability. However, certain morphological nuances were better captured in manual evaluations. The study discusses the implications of adopting CASA technology in clinical practice and emphasizes the need for standardization in semen analysis methodologies to enhance diagnostic accuracy.

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